Many Icelandics can be sensitive to sedation. Blessi usually takes about 1/3 the dosage recommended for his weight. Once, the vet gave him a full dosage and Blessi experienced breathing problems. For cases like Blessi, it is better to have the recommended dosage "to effect" permanently noted in your horse's vet records in case you forget to mention it to your vet.
Some Fjord horse owners have experienced the same problems with sedation. Here is a link to an article by a veterinarian experienced with the breed. He typically gives a lower dosage for this breed.
https://www.mail-archive.com/fjordhorse.../msg46358.html
This interesting sedation study by Pfizer Animal Health (note drug company for both humans and horses) indicates that the equine dentist or vet will lose money and time if they need to re-sedate during a procedure. Hummm..I would re-consider my use of a vet if he or she would not at least try to use a lower dose to start with.
https://www.zoetisus.com/_locale-assets/mcm-portal-assets/widgets/le/advantage/pdf/equine/dor0111001-the-cost-of-re-sedation.pdf
Here is a vet report that sedation dosages will very by both individual horses AND BY BREED with cold blooded breeds typically requiring less tranquilizer.
"Donkeys and mules typically respond differently to sedatives and tranquilizers. They tend to be less sensitive to the drugs and thus require higher doses to achieve the same effect. Different breeds and individual horses also show different sensitivity to these drugs. In general “hot bloods” like Arabians and Thoroughbreds require far more sedation than cold bloods (draft breeds), for the same effect."
http://horsesidevetguide.com/drv/Treatment/2/sedation-amp-tranquilization-generally/
Some Icelandics do well with suggested doses of sedation calculated by weight. But if you are new to Icelandics, talk to your vet about sedation dosages.
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